An aging-susceptible circadian rhythm controls cutaneous antiviral immunity

Aged skin is prone to viral infections, but the mechanisms responsible for this immunosenescent immune risk are unclear. We observed that aged murine and human skin expressed reduced levels of antiviral proteins (AVPs) and circadian regulators, including Bmal1 and Clock. Bmal1 and Clock were found t...

詳細記述

書誌詳細

出版年:	JCI Insight
主要な著者:	Stephen J. Kirchner, Vivian Lei, Paul T. Kim, Meera Patel, Jessica L. Shannon, David Corcoran, Dalton Hughes, Diana K. Waters, Kafui Dzirasa, Detlev Erdmann, Jörn Coers, Amanda S. MacLeod, Jennifer Y. Zhang
フォーマット:	論文
言語:	英語
出版事項:	American Society for Clinical investigation 2023-10-01
主題:	Aging Dermatology
オンライン･アクセス:	https://doi.org/10.1172/jci.insight.171548