PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts

Tumorigenic potential of human pluripotent stem cells (hPSCs) is an important issue in clinical applications. Despite many efforts, PSC-derived neural precursor cells (NPCs) have repeatedly induced tumors in animal models even though pluripotent cells were not detected. We found that polysialic acid...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Dongjin R. Lee, Jeong-Eun Yoo, Jae Souk Lee, Sanghyun Park, Junwon Lee, Chul-Yong Park, Eunhyun Ji, Han-Soo Kim, Dong-Youn Hwang, Dae-Sung Kim, Dong-Wook Kim
Format:	Article
Language:	English
Published:	Elsevier 2015-05-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671115001022