The AhR/IL-22 axis in chronic gut inflammation: unraveling mechanisms and therapeutic prospects

Chronic inflammatory bowel diseases, including Crohn’s disease (CD), ulcerative colitis (UC), and post-infectious irritable bowel syndrome (PI-IBS), are characterized by immune-mediated intestinal inflammation and epithelial barrier dysfunction. Research indicates that the aryl hydrocarbon receptor...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Huimin Kang, Zheng Chen, Baodong Wang, Zhiyun Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	the AhR/IL-22 pathway chronic intestinal inflammation immune response AhR IL-22
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1668173/full