Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells

This study used a nitroaliphatic chemistry approach to synthesize a novel artemisinin-derived carba-dimer (AG-1) and determined its anti-proliferative effects in human normal and cancer cells. AG-1 treatments selectively inhibit proliferation of cancer cells compared to normal human fibroblasts. Com...

詳細記述

書誌詳細

出版年:	Antioxidants
主要な著者:	Amanda L. Kalen, Brett A. Wagner, Ehab H. Sarsour, Maneesh G. Kumar, Jessica L. Reedy, Garry R. Buettner, Nabin C. Barua, Prabhat C. Goswami
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2020-01-01
主題:	artemisinin carba-dimer aliphatic nitro chemistry oxidative stress cyclin d1
オンライン･アクセス:	https://www.mdpi.com/2076-3921/9/2/108