Lenalidomide improves NKG2D-based CAR-T cell activity against colorectal cancer cells invitro

Introduction: Although CAR-based immunotherapy is viewed as a promising treatment for tumors, particularly hematological malignancies, solid tumors can pose challenges. It has been suggested that the immunomodulatory medication Lenalidomide (LEN) may increase the effectiveness of CAR T cells in the...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Mahdi Zarei, Shahriyar Abdoli, Touraj Farazmandfar, Majid Shahbazi
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	CAR-T cells NKG2D Colorectal cancer Lenalidomide
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023076685