Supramolecular Probe for Monitoring Lysosomal Ferritinophagy to Facilitate the Early Diagnosis of Parkinson's Disease

ABSTRACT Lysosomal iron overload, resulting from dysregulated ferritinophagy, is a significant early event in the progression of Parkinson's disease (PD). This condition causes iron accumulation within cells, triggering oxidative stress and ferroptosis, along with mitochondrial dysfunction and...

Full description

Bibliographic Details

Published in:	Aggregate
Main Authors:	Shiqin Zhou, Bo Xiao, Jiamin Chen, Jinming Zhu, Xia Ran, Zuoji Liu, Chaozhong Li, Li Wang, Xinai Cui, Rong Li, Guangwei Feng, Jian Feng
Format:	Article
Language:	English
Published:	Wiley 2025-09-01
Subjects:	ferritinophagy iron metabolism lysosomal targeting Parkinson's disease supramolecular probe
Online Access:	https://doi.org/10.1002/agt2.70120