Evidence of positively selected G6PD A‐ allele reduces risk of Plasmodium falciparum infection in African population on Bioko Island

Abstract Background Glucose‐6‐phosphate dehydrogenase (G6PD) is an essential enzyme that protects red blood cells from oxidative damage. Although G6PD‐deficient alleles appear to confer a protective effect of malaria, the link with clinical protection against Plasmodium infection is conflicting. Met...

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發表在:	Molecular Genetics & Genomic Medicine
Main Authors:	Xue‐Yan Liang, Jiang‐Tao Chen, Yan‐Bo Ma, Hui‐Ying Huang, Dong‐De Xie, Santiago‐m Monte‐Nguba, Carlos Salas Ehapo, Urbano Monsuy Eyi, Yu‐Zhong Zheng, Xiang‐Zhi Liu, Guang‐Cai Zha, Li‐Yun Lin, Wei‐Zhong Chen, Xia Zhou, Min Lin
格式:	Article
語言:	英语
出版:	Wiley 2020-02-01
主題:	EHH G6PD (A‐) deficiency malaria natural selection
在線閱讀:	https://doi.org/10.1002/mgg3.1061