Avian leukosis virus subgroup J evades innate immunity by activating miR-155 to dually target TRAF3 and STAT1.

Avian leukosis virus subgroup J (ALV-J) causes immunosuppression and myelocytomas in poultry. While ALV-J evades innate immunity to sustain infection, the mechanisms remain unclear. Here, we show that ALV-J upregulates microRNA-155 (miR-155) to suppress type I interferon (IFN-I) responses, facilitat...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Xinyue Zhang, Defang Zhou, Jing Zhou, Xiaoyang Liu, Longying Ding, Tianxing Yan, Mengyuan Shi, Shuhai He, Ziqiang Cheng
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-10-01
Online Access:	https://doi.org/10.1371/journal.ppat.1013552