PROTAC technology for the treatment of Alzheimer’s disease: advances and perspectives

Neurodegenerative diseases are characterized by the progression of neuronal degeneration, resulting in dysfunction of cognition and mobility. Many neurodegenerative diseases are due to proteinopathies arising from unusual protein accumulation and aggregation. The aggregation of misfolded proteins, s...

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Bibliographic Details

Published in:	Acta Materia Medica
Main Authors:	Hiroyuki Inuzuka, Jing Liu, Wenyi Wei, Abdol-Hossein Rezaeian
Format:	Article
Language:	English
Published:	Compuscript Ltd 2022-01-01
Subjects:	protac ubiquitin-proteasome system protein degradation autophagy alzheimer’s disease
Online Access:	https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2021-0001