Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing

Abstract Background Conotruncal heart defects (CTDs) are heterogeneous congenital heart malformations that result from outflow tract dysplasia; however, the genetic determinants underlying CTDs remain unclear. Increasing evidence demonstrates that dysfunctional TBX2 and TBX3 result in outflow tract...

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發表在:	Human Genomics
Main Authors:	Huilin Xie, Erge Zhang, Nanchao Hong, Qihua Fu, Fen Li, Sun Chen, Yu Yu, Kun Sun
格式:	Article
語言:	英语
出版:	BMC 2018-09-01
主題:	TBX2 TBX3 Variant Conotruncal heart defects Target sequencing
在線閱讀:	http://link.springer.com/article/10.1186/s40246-018-0176-0