May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells

In the decade since Yamanaka and colleagues described methods to reprogram somatic cells into a pluripotent state, human induced pluripotent stem cells (hiPSCs) have demonstrated tremendous promise in numerous disease modeling, drug discovery, and regenerative medicine applications. More recently, t...

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Bibliographic Details

Published in:	Cells
Main Authors:	Nicholas Brookhouser, Sreedevi Raman, Christopher Potts, David. A. Brafman
Format:	Article
Language:	English
Published:	MDPI AG 2017-02-01
Subjects:	human induced pluripotent stem cells (hiPSCs) genome editing homology-directed repair ZFN TALEN CRISPR/Cas9
Online Access:	http://www.mdpi.com/2073-4409/6/1/5