Accurate interpretation of p53 immunohistochemical patterns is a surrogate biomarker for TP53 alterations in large B-cell lymphoma

Abstract Background To clarify the relationship between p53 immunohistochemistry (IHC) staining and TP53 alterations (including mutations and deletions) in large B-cell lymphomas (LBCLs) and to explore the possibility of p53 IHC expression patterns as surrogate markers for TP53 alterations. Methods...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Xinyi Li, Danju Luo, Liling Zhang, Qiuhui Li, Jun Fan, Jiwei Zhang, Bo Huang, Ming Yang, Xiu Nie, Xiaona Chang, Huaxiong Pan
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	Lymphoma Large B-cell lymphoma p53 immunohistochemistry Surrogate marker TP53 alterations
Online Access:	https://doi.org/10.1186/s12885-023-11513-x