Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/β-Catenin Signaling

Statins improve recovery from traumatic brain injury and show promise in preventing Alzheimer disease. However, the mechanisms by which statins may be therapeutic for neurological conditions are not fully understood. In this study, we present the initial evidence that oral administration of simvasta...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Nicholas C. Robin, Zsuzsa Agoston, Travis L. Biechele, Richard G. James, Jason D. Berndt, Randall T. Moon
Format: Article
Language:English
Published: Elsevier 2014-01-01
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671113001276