Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium

Developmental defects of enamel are common due to genetic and environmental factors before and after birth. Cdc42, a Rho family small GTPase, regulates prenatal tooth development in mice. However, its role in postnatal tooth development, especially enamel formation, remains elusive. Here, we investi...

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Bibliographic Details

Published in:	Genes and Diseases
Main Authors:	Jinxuan Zheng, Rongcheng Yu, Yiqi Tang, Sihui Su, Sainan Wang, Chenxi Liao, Xuecong Li, Jiabin Liao, Dongsheng Yu, Tingting Ai, Wei Zhao, Vicky Yau, Chufeng Liu, Liping Wu, Yang Cao
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2024-09-01
Subjects:	Cdc42 Enamel defects Mitochondrial dysfunction Rho GTPase Tooth repair
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352304223004774