Preventing muscle wasting by osteoporosis drug alendronate in vitro and in myopathy models via sirtuin‐3 down‐regulation

Abstract Background A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise training and supportive therapies, a...

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Bibliographic Details

Published in:	Journal of Cachexia, Sarcopenia and Muscle
Main Authors:	Hsien‐Chun Chiu, Chen‐Yuan Chiu, Rong‐Sen Yang, Ding‐Cheng Chan, Shing‐Hwa Liu, Chih‐Kang Chiang
Format:	Article
Language:	English
Published:	Wiley 2018-06-01
Subjects:	Alendronate Skeletal muscle Atrophy Dysfunction Sirtuin3
Online Access:	https://doi.org/10.1002/jcsm.12289