Physiology and pharmacological targeting of phase separation

Abstract Liquid–liquid phase separation (LLPS) in biology describes a process by which proteins form membraneless condensates within a cellular compartment when conditions are met, including the concentration and posttranslational modifications of the protein components, the condition of the aqueous...

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Bibliographic Details
Published in:Journal of Biomedical Science
Main Authors: Fangfang Wang, Youwei Zhang
Format: Article
Language:English
Published: BMC 2024-01-01
Subjects:
Liquid–liquid phase separation (LLPS)
Condensates
Inclusion bodies
Pathogenic LLPS
Targeting LLPS
Online Access:https://doi.org/10.1186/s12929-024-00993-z

Internet

https://doi.org/10.1186/s12929-024-00993-z

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