Modulation of the PI3K/Akt signaling pathway by resveratrol in cancer: molecular mechanisms and therapeutic opportunity

Abstract The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a critical intracellular signaling pathway that is pivotal in various cellular functions. It is in senescence, survival, and growth under normal physiological and pathological conditions, including neoplasms. Additionally, this pathway...

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Bibliographic Details
Published in:Discover Oncology
Main Authors: Neda Hedayati, Mohamad Hosein Safari, Yaser Eshaghi Milasi, Samaneh Kahkesh, Najma Farahani, Seyedeh Mahdieh Khoshnazar, Zahra Dorostgou, Elmira Alaei, Mina Alimohammadi, Payman Rahimzadeh, Afshin Taheriazam, Mehrdad Hashemi
Format: Article
Language:English
Published: Springer 2025-05-01
Subjects:
Neoplasms
Phosphatidylinositol 3-kinase signal transduction
Proto-oncogene protein Akt
Resveratrol
Online Access:https://doi.org/10.1007/s12672-025-02471-w

Internet

https://doi.org/10.1007/s12672-025-02471-w

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