Prostaglandin E2 regulation of cyclooxygenase expression in keratinocytes is mediated via cyclic nucleotide-linked prostaglandin receptors

Inflammatory responses are thought to be mediated in part by the prostaglandins derived from arachidonic acid (AA) by the action of prostaglandin H synthase, also referred to as cyclooxygenase (COX). The mitogen-inducible isoform, COX-2, is over-expressed in numerous chronic inflammatory disease con...

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Bibliographic Details
Published in:Journal of Lipid Research
Main Authors: Regina E. Maldve, Youngsoo Kim, Stephanie J. Muga, Susan M. Fischer
Format: Article
Language:English
Published: Elsevier 2000-06-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320290