Parallel Palladium-Catalyzed Synthesis of Carboxylic Acids from Aryl Iodides, Bromides, and Vinyl Triflates Using Acetic Anhydride and Formate Anion as an External Condensed Source of Carbon Monoxide

Aryl iodides, bromides and vinyl-triflates are usually converted in high to excellent yields into the corresponding carboxylic acids through a parallel palladium-catalyzed hydroxycarbonylation using lithium formate and acetic anhydride as external condensed source of carbon monoxide.

Bibliographic Details

Published in:	Molecules
Main Authors:	Antonia Iazzetti, Giancarlo Fabrizi, Yuri Gazzilli, Antonella Goggiamani, Federico Marrone, Chen Shen, Roberta Zoppoli
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	palladium catalysis carbon monoxide carboxylic acid combinatorial chemistry
Online Access:	https://www.mdpi.com/1420-3049/30/15/3298