Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts

Fibrosis is a fundamental feature of systemic sclerosis (SSc) and is characterized by excessive accumulation of extracellular matrix components like proteoglycans (PG) or collagens in skin and internal organs. Serum analysis from SSc patients showed an increase in the enzyme activity of xylosyltrans...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Thanh-Diep Ly, Ricarda Plümers, Bastian Fischer, Vanessa Schmidt, Doris Hendig, Joachim Kuhn, Cornelius Knabbe, Isabel Faust
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Subjects:
activin A
fibrosis
MAPK
proteoglycan
Smad
systemic sclerosis
Online Access:https://www.mdpi.com/2218-273X/10/4/609

Internet

https://www.mdpi.com/2218-273X/10/4/609

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