Hyperkalemic effect of drug–drug interaction between esaxerenone and trimethoprim in patients with hypertension: a pilot study

Abstract Background We examined whether the pharmacodynamic drug–drug interaction between esaxerenone and trimethoprim enhances the hyperkalemic effect. Methods A retrospective observational study was conducted to identify patients >18 years undertaking esaxerenone alone or esaxerenone plus trime...

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Bibliographic Details

Published in:	Journal of Pharmaceutical Health Care and Sciences
Main Authors:	Toshinori Hirai, Shun Ueda, Toru Ogura, Kan Katayama, Kaoru Dohi, Yuki Kondo, Yuka Sakazaki, Yoichi Ishitsuka, Takuya Iwamoto
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	Drug–drug interaction Esaxerenone Trimethoprim Potassium Hyperkalemia
Online Access:	https://doi.org/10.1186/s40780-024-00366-6