Targeting CD47 as a therapeutic strategy: A common bridge in the therapy of COVID-19-related cancers

Macrophages are essential mediators of innate immunity. Non-self-cells resist phagocytosis through the expression of the checkpoint molecule CD47. CD47, as the integrin-associated protein, is overexpressed on tumor and SARS-CoV-2-infected cells as a potential surface biomarker for immune surveillanc...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Milad Zandi, Maryam Shafaati, Mohammad Shenagari, Hamed Naziri
Format:	Article
Language:	English
Published:	Elsevier 2023-07-01
Subjects:	CD47 SIRPα Phagocytosis Innate immunotherapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023051678