Evaluation of Rhenium and Technetium-99m Complexes Bearing Quinazoline Derivatives as Potential EGFR Agents

Τhe Epidermal Growth Factor Receptor tyrosine kinase inhibitor (EGFR-TKI) 6-amino-4-[(3-bromophenyl) amino]quinazoline was derivatized with 6-bromohexanoyl-chloride and coupled with the tridentate chelating agents N-(2-pyridylmethyl) aminoethyl acetic acid (PAMA) and <i>L</i>(+)-cysteine...

Full description

Bibliographic Details

Published in:	Molecules
Main Authors:	Konstantina Makrypidi, Christos Kiritsis, Ioanna Roupa, Sotiria Triantopoulou, Antonio Shegani, Maria Paravatou-Petsotas, Aristeidis Chiotellis, Maria Pelecanou, Minas Papadopoulos, Ioannis Pirmettis
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	EGFR TKI PAMA cysteine rhenium technetium-99m
Online Access:	https://www.mdpi.com/1420-3049/28/4/1786