GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer

BackgroundGlucosamine 6-phosphate N-acetyltransferase (GNPNAT1) is a crucial enzyme involving hexosamine biosynthesis pathway and is upregulated in breast cancer (BRCA). However, its biological function and mechanism on patients in BRCA have not been investigated.MethodsIn this study, the differenti...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Renjie Yuan, Yulu Zhang, Yange Wang, Hongling Chen, Ruiming Zhang, Zhiyuan Hu, Chengsen Chai, Tingmei Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	GNPNAT1 breast cancer biomarker tumor-infiltration immune cells immune checkpoints inhibitors immunotherapy response
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1152678/full