Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc
The homeobox transcription factors HoxA9 and Meis1 are causally involved in the etiology of acute myeloid leukemia. While HoxA9 alone immortalizes cells, cooperation with Meis1 is necessary to induce a full leukemic phenotype. Here, we applied degron techniques to elucidate the leukemogenic contrib...
| Published in: | Haematologica |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2022-05-01
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| Online Access: | https://haematologica.org/article/view/10643 |