Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging

Abstract Background In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure that provides quantitative labeling yields, diverse...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:EJNMMI Research
المؤلفون الرئيسيون: Elisabeth Eppard, Ana de la Fuente, Nicole Mohr, Mareli Allmeroth, Rudolf Zentel, Matthias Miederer, Stefanie Pektor, Frank Rösch
التنسيق: مقال
اللغة:الإنجليزية
منشور في: SpringerOpen 2018-02-01
الموضوعات:
DOTA-HPMA conjugates
Theranostic
Radiolabeling
Gallium-68
Scandium-44
Lutetium-177
الوصول للمادة أونلاين:http://link.springer.com/article/10.1186/s13550-018-0372-x

الانترنت

http://link.springer.com/article/10.1186/s13550-018-0372-x

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