Circulating miRNAs as potentially predictive biomarkers for chemoimmunotherapy in advanced biliary tract cancer: a post-hoc analysis of the phase II T1219 study

Abstract Circulating microRNAs (miRNAs) have not been investigated as predictive biomarkers in patients with advanced biliary tract cancer (ABTC) who received chemoimmunotherapy. In the single-arm phase II T1219 trial, 46 patients with ABTC received first-line nivolumab, gemcitabine, and S-1 treatme...

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Bibliographic Details

Published in:	npj Precision Oncology
Main Authors:	Nai-Jung Chiang, Cheng-Yu Tang, Li-Yuan Bai, Po-Chang Chang, Wei-Ming Chen, Shih-Ting Kang, San-Chi Chen, Ming-Huang Chen, Jason Chia-Hsun Hsieh
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Online Access:	https://doi.org/10.1038/s41698-025-01099-x