Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes

Background: In contrast to adults, Trypanosoma cruzi-infected children have more broadly functional Trypanosoma cruzi-specific T cells, and the total T-cell compartment exhibits fewer signs of immune exhaustion. However, not much is known about the link between immunocompetence and the treatment eff...

詳細記述

書誌詳細

出版年:	Frontiers in Immunology
主要な著者:	María C. Albareda, María A. Natale, Ana M. De Rissio, Marisa Fernandez, Alicia Serjan, María G. Alvarez, Gretchen Cooley, Huifeng Shen, Rodolfo Viotti, Jacqueline Bua, Melisa D. Castro Eiro, Myriam Nuñez, Laura E. Fichera, Bruno Lococo, Karenina Scollo, Rick L. Tarleton, Susana A. Laucella
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2018-09-01
主題:	Trypanosoma cruzi T cells benznidazole nifurtimox pediatric infection
オンライン･アクセス:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01958/full