Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein response (UPR). The most conserved pathway to trig...

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Bibliographic Details

Published in:	Emerging Microbes and Infections
Main Authors:	Cornelius Rohde, Stephan Becker, Verena Krähling
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-01-01
Subjects:	Marburg virus VP30 GP ER stress IRE1 XBP1
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2019.1659552