Irisin reduces senile osteoporosis by inducing osteocyte mitophagy through Ampk activation

Summary: Irisin, an exercise-induced myokine, is known to be able to regulate bone metabolism. However, the underlying mechanisms regarding the effects of irisin on senile osteoporosis have not been fully elucidated. Here, we demonstrated that irisin can inhibit bone mass loss and bone microarchitec...

Full description

Bibliographic Details

Published in:	iScience
Main Authors:	Honghan Li, Deqing Luo, Wei Xie, Wenbin Ye, Jinlong Chen, Paolo Alberton, Mingzhu Zhang, Eryou Feng, Denitsa Docheva, Dasheng Lin
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Subjects:	Biological sciences Physiology Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004224022673