Design of a multi-epitope vaccine against the pathogenic fungi Candida tropicalis using an in silico approach

Abstract Background Candida tropicalis causes tropical invasive fungal infections, with a high mortality. This fungus has been found to be resistant to antifungal classes such as azoles, echinocandins, and polyenes in several studies. As a result, it is vital to identify novel approaches to prevent...

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Bibliographic Details

Published in:	Journal of Genetic Engineering and Biotechnology
Main Authors:	Nahid Akhtar, Arshwinder Singh, Atul Kumar Upadhyay, M. Amin-ul Mannan
Format:	Article
Language:	English
Published:	Elsevier 2022-09-01
Subjects:	Antifungals Candidiasis Computational biology Epitope vaccine Molecular simulation Reverse vaccinology
Online Access:	https://doi.org/10.1186/s43141-022-00415-3