Maternal Western-style diet has a persistent effect on offspring gene expression in skeletal muscle of Japanese macaques

Abstract The cellular mechanisms underlying a greater risk of cardiometabolic disease in adult offspring exposed to maternal obesity are not known. Our prior work found reduced skeletal muscle mitochondrial metabolism and insulin sensitivity in offspring exposed to maternal (m) Western-style diet (W...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Emily A. Beck, Byron Hetrick, Luis Nassar, Douglas W. Turnbull, Tyler A. Dean, Diana L. Takahashi, Maureen Gannon, Stephanie R. Wesolowski, Kjersti M. Aagaard, Jacob E. Friedman, Paul Kievit, Carrie E. McCurdy
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-07-01
Subjects:	Metabolic programming Maternal diet Offspring Skeletal muscle Gene expression Maternal obesity
Online Access:	https://doi.org/10.1038/s41598-025-00828-3