Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT
Cell adhesion is important in cancer metastasis. Malignant cells in cancer patients may be exposed to physical forces such as extracellular pressure and shear, that stimulate their adhesion to matrix proteins, endothelium and surgical wounds. Pressure induces phosphorylation of AKT and focal adhesio...
| Published in: | Cellular Oncology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0469 |