Effects of ketamine on fear memory extinction: a review of preclinical literature

IntroductionKetamine, a multimodal dissociative anesthetic, is widely used as a trauma analgesic in emergency situations. Ketamine is also used to treat psychiatric disorders due to its broad application potential, including treatment-resistant major depression. However, its impacts on the developme...

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Bibliographic Details

Published in:	Frontiers in Neuroscience
Main Authors:	Martin Boese, Rina Berman, Kennett Radford, Luke R. Johnson, Kwang Choi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	ketamine fear memory posttraumatic stress disorder (PTSD) fear extinction cognitive behavioral therapy (CBT) review
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1546460/full