Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer
Abstract Background Most molecular classifications of cancer are based on bulk-tissue profiles that measure an average over many distinct cell types. As such, cancer subtypes inferred from transcriptomic or epigenetic data are strongly influenced by cell-type composition and do not necessarily refle...
| Published in: | Genome Medicine |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13073-025-01453-5 |