A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies

Background: Dementia with Lewy bodies (DLB) is the second most common age-related neurocognitive pathology after Alzheimer's disease. Animal models characterizing this disease are lacking and their development would ameliorate both the understanding of neuropathological mechanisms underlying DL...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Estelle Schueller, Iris Grgurina, Brigitte Cosquer, Elodie Panzer, Noémie Penaud, Anne Pereira de Vasconcelos, Aline Stéphan, Karine Merienne, Jean-Christophe Cassel, Chantal Mathis, Frédéric Blanc, Olivier Bousiges, Anne-Laurence Boutillier
Format:	Article
Language:	English
Published:	Elsevier 2024-10-01
Subjects:	Dementia with Lewy bodies Transgenic mouse model α-Synuclein Prodromal stage Human cohort Frontal cortex
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996124002766