Indoleamine-2,3-Dioxygenase as a Perioperative Marker of the Immune System

Indoleamine-2,3-dioxygenase (IDO) is the “rate-limiting” enzyme in the kynurenine (Kyn) pathway of the tryptophan (Trp) catabolism. By its immune-modulatory effect, IDO initiates changes to the physiologically balanced immune state and plays a key role in the pathogenesis of various diseases, as wel...

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Bibliographic Details
Published in:Frontiers in Physiology
Main Authors: Corina Bello, Paul Philipp Heinisch, Maks Mihalj, Thierry Carrel, Markus M. Luedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Subjects:
immune system
cardiac surgery
indoleamine-2
3-dioxygenase
tryptophan
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.766511/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.766511/full

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