Acetylation is required for full activation of the NLRP3 inflammasome

Abstract Full activation of the NLRP3 inflammasome needs two sequential signals: a priming signal, followed by a second, assembly signal. Several studies have shown that the two signals trigger post-translational modification (PTM) of NLRP3, affecting activity of the inflammasome, however, the PTMs...

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出版年:	Nature Communications
主要な著者:	Yening Zhang, Ling Luo, Xueming Xu, Jianfeng Wu, Fupeng Wang, Yanyan Lu, Ningjie Zhang, Yingying Ding, Ben Lu, Kai Zhao
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2023-12-01
オンライン･アクセス:	https://doi.org/10.1038/s41467-023-44203-0