The DNA repair kinase ATM regulates CD13 expression and cell migration

Classically, ATM is known for its role in sensing double-strand DNA breaks, and subsequently signaling for their repair. Non-canonical roles of ATM include transcriptional silencing, ferroptosis, autophagy and angiogenesis. Angiogenesis mediated by ATM signaling has been shown to be VEGF-independent...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Louise K. Stevenson, Amy J. Page, Matthew Dowson, Sameh K. ElBadry, Francis M. Barnieh, Robert A. Falconer, Sherif F. El-Khamisy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	aminopeptidase-N CD13 ATM cell migration angiogenesis DNA repair
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1359105/full