CD8+CD122+ T cell homeostasis is controlled by different levels of IL-15 trans-presentation

The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentati...

Full description

Bibliographic Details
Published in:Journal of Microbiology, Immunology and Infection
Main Authors: Gilbert Aaron Lee, Nan-Shih Liao
Format: Article
Language:English
Published: Elsevier 2021-06-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118220301468