An Efficient Synthesis of Arylated Pyridines from Conjugated Acetylenes and Substituted Benzylamines Catalyzed by Base

An efficient base-catalyzed synthesis of arylated pyridines has been disclosed. This reaction involving conjugated acetylenes and substituted benzylamines proceeded smoothly, giving rise to tri-aryl substituted pyridines which are biologically relevant compounds in good to excellent yields in N,N-di...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Mengping Guo, Bo Chen, Qiming Zhu, Hua Jin, Qiuling Peng, Yanping Kang
Format:	Article
Language:	English
Published:	MDPI AG 2017-07-01
Subjects:	arylated pyridines synthesis transition-metal-free base catalysis
Online Access:	https://www.mdpi.com/1420-3049/22/8/1277