Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues and is exposed to new selective pressures, thus, potentially driving adaptive evolution. Previous studies have shown the key role of the agr locus in S. aureus pathoadaptation; however, a more compre...

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Bibliographic Details

Published in:	eLife
Main Authors:	Stefano G Giulieri, Romain Guérillot, Sebastian Duchene, Abderrahman Hachani, Diane Daniel, Torsten Seemann, Joshua S Davis, Steven YC Tong, Bernadette C Young, Daniel J Wilson, Timothy P Stinear, Benjamin P Howden
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2022-06-01
Subjects:	within-host evolution adaptation Staphylococcus aureus genomics
Online Access:	https://elifesciences.org/articles/77195