Macrophage Infiltration Initiates RIP3/MLKL-Dependent Necroptosis in Paclitaxel-Induced Neuropathic Pain

Paclitaxel (PTX) is a commonly used antitumor drug. Approximately 80% of all patients receiving PTX chemotherapy develop chemotherapy-induced peripheral neuropathy (CIPN), limiting the use of PTX. Moreover, CIPN responds poorly to conventional analgesics. Experimental evidence suggests that the neur...

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Bibliographic Details

Published in:	Mediators of Inflammation
Main Authors:	Dongyang Ma, Xiuli Wang, Xin Liu, Zhao Li, Jiaxin Liu, Jing Cao, Guiying Wang, Yuexian Guo, Shuang Zhao
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Online Access:	http://dx.doi.org/10.1155/2022/1567210