Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis

Peritoneal fibrosis (PF) is a major cause of ultrafiltration failure in long-term peritoneal dialysis (PD) patients. Nevertheless, limited measures have been shown to be effective for the prevention and treatment of PF. Some views reveal that activation of autophagy ameliorates PF but others demonst...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Yingfeng Shi, Yan Hu, Yi Wang, Xiaoyan Ma, Lunxian Tang, Min Tao, Andong Qiu, Shougang Zhuang, Na Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Subjects:	autophagy peritoneal fibrosis epithelial to mesenchymal transition profibrotic signaling pathways inflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.724141/full