HIV-1 Gag targeting to the plasma membrane reorganizes sphingomyelin-rich and cholesterol-rich lipid domains

Abstract Although the human immunodeficiency virus type 1 lipid envelope has been reported to be enriched with host cell sphingomyelin and cholesterol, the molecular mechanism of the enrichment is not well understood. Viral Gag protein plays a central role in virus budding. Here, we report the inter...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Nario Tomishige, Maaz Bin Nasim, Motohide Murate, Brigitte Pollet, Pascal Didier, Julien Godet, Ludovic Richert, Yasushi Sako, Yves Mély, Toshihide Kobayashi
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Online Access:	https://doi.org/10.1038/s41467-023-42994-w