Culture at a Higher Temperature Mildly Inhibits Cancer Cell Growth but Enhances Chemotherapeutic Effects by Inhibiting Cell-Cell Collaboration.

Acute febrile infections have historically been used to treat cancer. To explore the underlying mechanism, we studied chronic effects of fever on cancer cell growth and chemotherapeutic efficacy in cell culture. We found that culturing cancer cells at 39°C mildly inhibited cell growth by arresting t...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Shengming Zhu, Jiangang Wang, Bingkun Xie, Zhiguo Luo, Xiukun Lin, D Joshua Liao
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Online Access:	http://europepmc.org/articles/PMC4619682?pdf=render