Loss of protein tyrosine phosphatase receptor delta PTPRD increases the number of cortical neurons, impairs synaptic function and induces autistic-like behaviors in adult mice

Abstract Background The brain cortex is responsible for many higher-level cognitive functions. Disruptions during cortical development have long-lasting consequences on brain function and are associated with the etiology of brain disorders. We previously found that the protein tyrosine phosphatase r...

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書誌詳細

出版年:	Biological Research
主要な著者:	Bastián I. Cortés, Rodrigo C. Meza, Carlos Ancatén-González, Nicolás M. Ardiles, María-Ignacia Aránguiz, Hideaki Tomita, David R. Kaplan, Francisca Cornejo, Alexia Nunez-Parra, Pablo R. Moya, Andrés E. Chávez, Gonzalo I. Cancino
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-06-01
主題:	Protein tyrosine phosphatase receptor delta Medial prefrontal cortex Synaptic transmission Anxiety Learning Memory
オンライン･アクセス:	https://doi.org/10.1186/s40659-024-00522-0