Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
BACKGROUND: The transient receptor potential ankyrin 1 (TRPA1) channel, localized to airway sensory nerves, has been proposed to mediate airway inflammation evoked by allergen and cigarette smoke (CS) in rodents, via a neurogenic mechanism. However the limited clinical evidence for the role of neuro...
| 發表在: | PLoS ONE |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Public Library of Science (PLoS)
2012-01-01
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| 在線閱讀: | http://europepmc.org/articles/PMC3419223?pdf=render |
