Study on molecular mechanism of intervertebral disc degeneration by single cell hdWGCNA combined with transcriptome sequencing

Background: Intervertebral disc degeneration (IVDD) is one of the important causes of lower back pain, seriously affecting people's health and quality of life. This research employs single-cell analysis to identify the specific cellular subtypes and key regulatory genes associated with IVDD. Me...

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Bibliographic Details

Published in:	Non-coding RNA Research
Main Authors:	Xuan Zhao, Qijun Wang, Wei Wang, Xiaolong Chen, Shibao Lu
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-02-01
Subjects:	Intervertebral disc degeneration Single cell analysis hdWGCNA Machine learning Diagnostic markers
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468054024001379