Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation

Age alters the host’s susceptibility to immune induction. Humoral immunity with circulating antibodies, particularly immunoglobulin G (IgG), plays an essential role in immune response. IgG glycosylation in the fragment crystallizable (Fc) region, including sialylation, is important in regulating the...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Priti Gupta, Tibor Sághy, Miriam Bollmann, Tao Jin, Claes Ohlsson, Hans Carlsten, Carmen Corciulo, Cecilia Engdahl
Format:	Article
Language:	English
Published:	MDPI AG 2024-04-01
Subjects:	humoral immune response IgG age antigen-induced arthritis IgG-sialylation
Online Access:	https://www.mdpi.com/2076-393X/12/5/479